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Dr. LI Shirley X.
PhD, DClinPsy, CPsychol
Assistant Professor

LI_Shirley

Education
Honours. B.Sc (University of Toronto)
M.A. (The Chinese University of Hong Kong)
Ph.D (The Chinese University of Hong Kong)
D.Clin.Psy (University College London)

 

Contacts
Office: 6.63
Phone: (852)3917-7035
Email: shirley.li@hku.hk
HKU Researcher Page: http://hub.hku.hk/cris/rp/rp02114
Research Lab: Sleep Research Laboratory
Research Clinic: Sleep Research Clinic

Research Interests
Sleep disorders
Sleep and psychopathology
Sleep and cognition
Affective disorders, psychosis

Selected Publications
Li SX, Chan NY, Yu MWM, Lam SP, Zhang J, Chan JWY, Li AM, Wing YK. Eveningness chronotype, insomnia symptoms and emotional and behavioural problems in adolescents. Sleep Medicine [In press]

Li SX, Lam SP, Zhang J, Yu MWM, Chan JWY, Chan CSY, Espie CA, Freeman D, Mason O, Wing YK. Sleep disturbances and suicide risk in an 8-year longitudinal study of schizophrenia-spectrum disorders. Sleep 2016;39:1275-1282.

Li SX, Lam SP, Zhang J, Yu MWM, Chan JWY, Liu Y, Lam VKH, Ho CKW, Zhou J, Wing YK. A prospective naturalistic follow-up study of treatment outcome with clonazepam in REM sleep behavior disorder. Sleep Med 2016;21:114-120

Li SX, Lam SP, Wing YK. Looking beyond the sleep complaints: a link to suicidality. J Clin Psychiatry 2013;74:192.

Li SX, Lam SP, Chan JWY, Yu MWM, Wing YK. Residual sleep disturbances in patients remitted from major depressive disorder – A 4-year naturalistic follow-up study. Sleep 2012;35:1153-61.

Li SX, Yu MWM, Lam SP, Zhang J, Li AM, Lai KYC, Wing YK. Frequent nightmares in children: familial aggregation and associations with parent-reported behavioral and mood problems. Sleep 2011;34:487-493.

Li SX, Lam SP, Yu MWM, Zhang J, Wing YK. Nocturnal sleep disturbances as a predictor of suicide attempts among psychiatric outpatients. J Clin Psychiatry 2010;71:1440-6.

Li SX, Zhang B, Li AM, Wing YK. Prevalence and correlates of recurrent nightmares: a community-based two-phase study. Sleep 2010;33:774-80.

Li SX, Wing YK, Lam SP, et al. Validation of a new REM sleep behavior disorder questionnaire (RSBDQ-HK). Sleep Med 2010;11:43-8.

Sun W, Li SX, Wang G, Dong S, Jiang Y, Spruyt K, Ling J, Zhu Q, Lee TMC, Jiang F. Association of sleep and circadian activity rhythm with emotional face processing among 12-month-old infants. Scientific Reports 2018;8(1):3200.

Chan NY, Zhang J, Yu MWM, Lam SP, Li SX, Kong APS, Li AM, Wing YK. Impact of a modest delay in school start time in school adolescents. Sleep Medicine 2017,30:164-170.

Zhou J, Zhang J, Lam SP, Chan JWY, Mok V, Chan A, Li SX, Liu Y, Tang X, Yung WH, Wing YK. Excessive daytime sleepiness predicts neurodegeneration in idiopathic REM sleep behavior disorder. Sleep 2017;40(5). doi: 10.1093/sleep/zsx041.

Zhang J, Liu Y, Lam SP, Li SX, Li AM, Wing YK. Relationship between insomnia and quality of life. Heart Mind 2017;1:50-5.

Zhang J, Chan NY, Lam SP, Li SX, Liu Y, Chan JWY, Kong APS, Ma RCW, Chan KCC, Li AM, Wing, YK. Emergence of sex differences in insomnia symptoms in adolescents: a large-scale school-based study. Sleep 2016 Apr 12. pii: sp-00724-15.

Liu Y, Zhang J, Lam SP, Yu MWM, Li SX, Zhou J, Chan JWY, Chan NY, Li AM, Wing YK. Help-seeking behaviors for insomnia in Hong Kong Chinese – A community-based study. Sleep Med 2016;21:106-113

Zhang J, Lam S, Kong APS, Ma RCW, Li SX, Chan WY, Yu MWM, Zhou J, Chan MHM, Ho C, Li AM, Tang X, Wing YK. Family conflict and lower morning cortisol in adolescents and adults: modulation of puberty. Sci Rep  2016 Mar 1;6:22531. doi: 10.1038/srep22531.

Chan NY, Lam SP, Zhang J, Yu MWM, Li SX, Li AM, Wing YK. Sleep education in Hong Kong. Sleep Biol Rhythms 2016;14:21-25.

Wing YK, Chan NY, Yu Man MW, Lam SP, Zhang J, Li SX, Kong AP, Li AM. A school-based sleep education program for adolescents: a cluster randomized trial. Pediatrics 2015;135:e635-43.

Wing YK, Lam SP, Zhang JH, Leung E, Ho CL, Chen, S, Cheung MK, Li SX, Chan JWY, Mok V, Tsoh J, Chan A, Ho CKW. Reduced striatal dopamine transmission in REM sleep behavior disorder co-morbid with depression, Neurology 2015;84:516-22.

Chan JW, Lam SP, Li SX, Yu MW, Chan NY, Zhang J, Wing YK. Eveningness and insomnia: independent risk factors of nonremission in major depressive disorder. Sleep 2014;37:911-7.

Zhang J, Lam SP, Li SX, Ma RC, Kong AP, Chan MH, Ho CS, Li AM, Wing YK. A community-based study on the association between insomnia and hypothalamic-pituitary-adrenal axis: sex and pubertal influences. J Clin Endocrinol Metal 2014; 99:2277-87.

Zhang J, Lam SP, Li SX, Li AM, Kong AP, Wing Y. Restless legs symptoms in adolescents: Epidemiology, heritability, and pubertal effects. J Psychosom Res 2014;76:158-64.

Lam SP, Li SX, Zhang J, Wing YK. Development of scales for assessment of REM sleep behavior disorder (RBD). Sleep Med 2013;14:734-8.

Lam SP, Li SX, Chan JWY, Mok V, Tsoh J, Chan A, Yu MWM, Lau CY, Zhang J, Lam V, Ho CK, Wing YK. Does REM sleep behavior disorder exist in psychiatric populations? A clinical and polysomnographic case-control study. Sleep Med 2013;14:788-94.

Wing YK, Zhang J, Lam SP, Li SX, Tang NL, Lai KY, Li AM. Familial aggregation and heritability of insomnia in a community-based study. Sleep Med 2012;13:985-90.

Wing YK, Li SX, Mok V, Lam SP, Tsoh J, Chan A, Yu MWM, Lau CYK, Zhang J, Ho CKW. Prospective outcome of rapid eye movement sleep disorder: psychiatric disorders as a potential early marker of Parkinson’s disease. J Neurol Neurosurg Psychiatry 2012;83:470-2

Zhang J, Lam SP, Li SX, Tang NL, Yu MWM, Li AM, Wing YK. Insomnia, sleep quality, pain and somatic symptoms: sex differences and shared genetic components. Pain 2012;153:666-73

Zhang J, Lam SP, Li SX, Yu MWM, Li AM, Ma RCW, Kong ASP, Wing YK. Long-term outcomes and predictors of chronic insomnia: a prospective study in Hong Kong Chinese adults. Sleep Med 2012;13:455-62

Lam SP, Li SX, Mok V, Wing YK. Young-onset REM sleep behavior disorder: Beyond the antidepressant effect. Sleep Med 2012;13:211

Zhang J, Lam SP, Li SX, Li AM, Wing YK. The longitudinal course and impact of non-restorative sleep: a five-year community-based follow-up study. Sleep Med 2012;13:570-6.

Zhang J, Lam S, Li SX, Li AM, Lai KYC, Wing YK. Longitudinal course and outcome of chronic insomnia in Hong Kong Chinese children: A 5-year follow-up study of a community-based cohort. Sleep 2011;34:1395-1402.

KNOWLEDGE EXCHANGE PROJECTS

  1. Parent-Based Sleep Education for Children with Autism Spectrum Disorders
    This project aims to provide sleep education to support and equip parents of children with autism spectrum disorders with the necessary knowledge and strategies to manage their child’s sleep problems and help to improve their child’s sleep and health.
  1. Sleep for Health – A Community-based Sleep Health Promotion Programme
    The project aims to disseminate sleep-related health knowledge in the community in order to raise the public’s awareness towards the importance of sleep and to increase the public’s understanding about common sleep problems and adequate sleep hygiene practice

RESEARCH INTERNSHIP OPPORTUNITIES (2018-2019)
Research projects:

We have a series of research projects available for ambitious and highly motivated students who want to gain hands-on research experiences: 

  1. The impacts of irregular sleep-wake patterns on cognitive and emotional functioning
    Main duties: contacting potential participants through telephone, conducting manipulation check by sending messages to participants, conducting overnight polysomnographic (PSG) sleep assessment (PSG hook up, monitoring overnight PSG recording), administration of computerized tasks, and data management
  2. The effects of memory reactivation during sleep on false memory formation
    Main duties: contacting potential participants through telephone, administering interviews and questionnaires, conducting polysomnographic (PSG) sleep assessment (PSG hook up, monitoring PSG recording), administration of computerized tasks, and data management
  3. Insomnia and depression treatment study in adolescents and young adults
    Main duties: contacting research participants by telephone interview (adolescents), administering computerized tasks and questionnaires to the participants, data entry and data management
  4. Sleep and circadian rhythm study on offsprings of patients with bipolar disorder
    Main duties: contacting research participants by telephone interview (adolescents), recruiting participants and collecting data, administering questionnaires to participants, data entry and data management
  5. Sleep disturbances in children and adolescents with ADHD
    Main duties: recruiting participants and collecting data in an outpatient clinic of a public hospital, administering questionnaires to participants, data entry and data management, scheduling participants for treatment, and preparing treatment materials.
  6. The effects of sleep deprivation on cognitive and visuomotor performance
    Main duties: recruiting participants and collecting data (overnight shift involved) - administering interview, questionnaires and computerised tasks with participants, experimental setup for eye tracking data acquisition, and data management
  7. Impacts of insomnia in adolescents and young adults – A neurocognitive perspective
    Main duties: recruiting participants and collecting data - administering interview, questionnaires and computerised tasks with participants, experimental setup for EEG data acquisition, and data management

Interns will be working collaboratively as a member of the research team, being involved in different aspects of the above research projects (e.g. conducting literature review, study recruitment, administering computerized tasks, data entry and data management). They will be expected to travel to the recruitment sites, and to attend and actively participate in supervision meetings and research meetings where we discuss our ongoing projects or the current issues in the field of sleep research. Interns may also participate in guided readings of the sleep-related literature.

Intern Selection:
Academic excellence
Highly motivated to gain research experiences and able to commit
Conscientious, organized and good interpersonal skills
Proficiency in both Chinese and English
Knowledge of Excel and SPSS is preferable

Interns may work in clinical settings, and as such must be mature, articulate and comfortable communicating with others. Successful candidates would also need to be able to demonstrate enthusiasm for the research being conducted, a strong work ethic and ability to work in a highly collaborative, multidisciplinary team-oriented environment.

Priority will be given to the individuals who are flexible with schedule (preferably at least one day or no less than 10-12 hours per week) and with potential for longer term involvement. For the upcoming academic year 2018-2019, being able to take up at least one overnight shift to monitor sleep assessment may be expected for the interns.

SUMMER RESEARCH INTERNSHIP 2018
Undergraduate students who are interested in gaining research experiences during the summer 2018 may consider applying to join our research team and work as a research intern in the lab on a voluntary basis. Priority will be given to the individuals who are flexible with schedule and are able to commit to the research work on a regular basis (e.g. at least 3 days per week for at least 2 months - preferably 3 months, during May to early September 2018). In addition, being able to take up at least one or two overnight shifts during the week to monitor the sleep studies plus daytime lab duties (see the research projects listed above) are expected for the interns. As relevant training will be provided in May-June, please apply for this internship as early as possible if you are interested.

How to apply:
If you are interested in joining us, please send an updated CV, transcript and personal statement to Dr Shirley Li (shirley.li@hku.hk).

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